115540-28-8Relevant articles and documents
A calcitriol synthesis of intermediates method
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, (2019/06/13)
The invention discloses a calcitriol intermediate compound preparation method, which belongs to the drug synthesis and organic compound synthesis technology field. The invention wide sources of raw materials are easy, simple and safe operation, environmen
Synthesis of 24(28)-methylene-1α-hydroxyvitamin D3, a novel vitamin D3 analogue
Guo, Wei,Fang, Zhijie,Li, Hongliang,Liu, Yanan
, p. 231 - 235 (2014/05/06)
24(28)-Methylene-1α-hydroxyvitamin D3 was synthesised in 13 steps from vitamin D2. The key step of the synthesis involved the Wittig-Horner olefination of a nor-vitamin D2 aldehyde with diethylphosphono-3-methyl-2-butanone
Synthesis of a Biologically Active Vitamine-D2 Metabolite
Choudhry, Satish C.,Belica, Peter S.,Coffen, David L.,Focella, Antonino,Maehr, Hubert,et al.
, p. 1496 - 1500 (2007/10/02)
The synthesis of 1α,25,28-trihydroxyvitamin-D2 (1) from vitamin-D2 is described.Approaches to the upper side-chain synthon via the chiral sulfone 15, prepared either through the enzymatic resolution of 10 or the opening of the optica