115550-35-1 Usage
Brand Name(s) in US
Zeniquin, Marbocyl
Description
Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.
Chemical Properties
Crystalline Solid
Uses
Different sources of media describe the Uses of 115550-35-1 differently. You can refer to the following data:
1. Fluorinated quinolone antibacterial
2. A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species
Definition
ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect
um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood.
Veterinary Drugs and Treatments
Marbofloxacin is labeled for the treatment of susceptible bacterial
infections in dogs and cats.
Check Digit Verification of cas no
The CAS Registry Mumber 115550-35-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,5,5 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 115550-35:
(8*1)+(7*1)+(6*5)+(5*5)+(4*5)+(3*0)+(2*3)+(1*5)=101
101 % 10 = 1
So 115550-35-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)