115579-08-3

Basic information

• Product Name: 2-Propanone, 1-(1,3,2-dioxaphosphorinan-2-yl)-, P-oxide
• CAS NO: 115579-08-3
• Molecular Formula: C6H11O4P
• Molecular Weight: 178.125
• Mol File: 115579-08-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propanone, 1-(1,3,2-dioxaphosphorinan-2-yl)-, P-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanone, 1-(1,3,2-dioxaphosphorinan-2-yl)-, P-oxide(115579-08-3)
• EPA Substance Registry System: 2-Propanone, 1-(1,3,2-dioxaphosphorinan-2-yl)-, P-oxide(115579-08-3)

Safety Data

• Hazardous Substances Data: 115579-08-3(Hazardous Substances Data)

Upstream product

• 113977-43-8 2-benzyloxy-1,3,2-dioxaphosphorinane 
• 598-31-2 1-bromoacetone 

Downstream Products

• 115579-31-2 (Z)-3-(2-Oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-4-(2-trifluoromethyl-phenyl)-but-3-en-2-one 
• 115578-81-9 2-[1-(2-trifluoromethylbenzylidene)acetonyl]-2-oxo-1,3,2-dioxaphosphorinane 
• 102097-75-6 methyl 2,6-dimethyl-4-(3-nitrophenyl)-5-(2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydropyridine-3-carboxylate 
• 102097-78-9 methyl 2,6-dimethyl-4-(2-nitrophenyl)-5-(2-oyo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydropyridine-3-carboxylate 
• 102098-24-8 2-(N-Benzyl-N-methylamino)-ethyl 4-(2-difluoromethoxyphenyl)-2,6-dimethyl-5-(2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydropyridine-3-carboxylate 
• 102097-76-7 2-(N-benzyl-N-methylamino)ethyl 2,6-dimethyl-4-(3-nitrophenyl)-5-(2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydropyridine-3-carboxylate 
• 102098-22-6 4-(2-Difluoromethoxy-phenyl)-2,6-dimethyl-5-(2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-1,4-dihydro-pyridine-3-carboxylic acid methyl ester 
• 102098-25-9 methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-5-(2-oxo-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydropyridine-3-carboxylate 
• 115579-30-1 (Z)-4-(2-Nitro-phenyl)-3-(2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-but-3-en-2-one 
• 115578-80-8 2-(1-(2-Nitrobenzylidene)-acetonyl)-2-oxo-1,3,2-dioxaphosphorinane 
• 1540-94-9 N-isobutylacetamide 
• 115550-22-6 1-<1-(2-nitrobenzylidene)acetonyl>-2-oxo-1,3,2-dioxaphosphorinane 
• 115578-79-5 2-(1-(3-nitrobenzylidene)acetonyl)-2-oxo-1,3,2-dioxaphosphorinane 
• 115578-83-1 (E)-4-(2,3-Dichloro-phenyl)-3-(2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-but-3-en-2-one 

Relevant articles and documents

Reaction of Cyclic Phosphites with Haloacetones

Treatment of various cyclic phosphites (1), e.g.,2-methoxy-1,3,2-dioxaphosphorinane (1a), 2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane (1b) and 2-methoxy-1,3,2-dioxaphosphorane (1c), with haloacetones (2) gave cyclic Arbuzov products (3), cyclic Perkow products (4), cyclic methylphosphonates (5), and acyclic products (6-8).Compound 1a gave all of the products (3a,4a,5a,6ag,7ag,8ag).However, cyclic phosphites with substituents in the ring (1b,1d) gave only the cyclic products (3-5).The five -membered ring phosphite (1c) yielded only the acyclic products (6cg, 7cg).Treatment of 1a with chloroacetone gave only the Perkow products (4a,7ah).Cyclic phosphite (1f)with 2-benzyloxy substituenet afforded simply the cyclic products (3a, 4a, 9).A mechanistic interpretation of these reactions is presented. Keywords---cyclic phosphite; haloacetone; cyclic acetonylphosphonate; cyclic enol phosphate; Arbuzov reaction; Perkow reaction