1155800-54-6 Usage
Uses
4-Amino-5-nitro-2-(trifluoromethyl)benzonitrile, can be used in the synthesis of substituted benzene-1,2-diamines, which are functional building blocks for the preparation of biologically active heterocyclic molecules, such as, 2,5,6-trisubstitued benzimidazole derivatives as selective androgen receptor modulators (SARMs),
Check Digit Verification of cas no
The CAS Registry Mumber 1155800-54-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,5,8,0 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1155800-54:
(9*1)+(8*1)+(7*5)+(6*5)+(5*8)+(4*0)+(3*0)+(2*5)+(1*4)=136
136 % 10 = 6
So 1155800-54-6 is a valid CAS Registry Number.
1155800-54-6Relevant articles and documents
An efficient synthetic process for scale-up production of 4,5-diamino-2- (trifluoromethyl)benzonitrile and 5-bromo-3-(trifluoromethyl)benzene-1,2-diamine
Li, Xun,Ng, Raymond A.,Zhang, Yongzheng,Russell, Ronald K.,Sui, Zhihua
experimental part, p. 652 - 655 (2010/04/22)
Starting from 4-amino-2-(trifluoromethyl)benzonitrile (6), an efficient and nonchromatographic process was developed for multihundred gram production of 4,5-diamino-2-(trifluoromethyl)- benzonitrile (1) in 73% yield and 98 HPLC area% purity over four synthetic steps. The same synthetic strategy was applied to 4-bromo-2-(trifluoromethyl)aniline (7) that afforded 5-bromo-3- (trifluoromethyl)benzene-1,2-diamine (5) in 81% overall yield and 99% HPLC area% purity.
