115581-44-7

Basic information

• Product Name: (2-Chloro-5-methylsulfanyl-pyrimidin-4-yl)-(4-methoxy-benzyl)-amine
• Synonyms: (2-Chloro-5-methylsulfanyl-pyrimidin-4-yl)-(4-methoxy-benzyl)-amine
• CAS NO: 115581-44-7
• Molecular Weight: 295.793
• Mol File: 115581-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-Chloro-5-methylsulfanyl-pyrimidin-4-yl)-(4-methoxy-benzyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Chloro-5-methylsulfanyl-pyrimidin-4-yl)-(4-methoxy-benzyl)-amine(115581-44-7)
• EPA Substance Registry System: (2-Chloro-5-methylsulfanyl-pyrimidin-4-yl)-(4-methoxy-benzyl)-amine(115581-44-7)

Safety Data

• Hazardous Substances Data: 115581-44-7(Hazardous Substances Data)

Upstream product

• 24795-76-4 2,4,6-trichloro-5-methylthio-pyrimidine 
• 2393-23-9 4-methoxy-benzylamine 
• 7401-98-1 2,4-dichloro-5-methylsulfanylpyrimidine 

Downstream Products

• 115581-45-8 (4-Methoxy-benzyl)-(5-methylsulfanyl-pyrimidin-4-yl)-amine 

Relevant articles and documents

The anti-H1-histaminic and antimuscarinic effect of 2- and 4-[benzyl-(2-dimethylaminoethyl)amino]pyrimidine compounds

This paper reports the synthesis of 2- and 4- [benzyl-(2-dimethylaminoethyl)amino]pyrimidine compounds and the evaluation of their inhibitory properties against histamine (H1), acetylcholine and barium chloride, on guinea pig isolated ileum. 4-[p.Methoxybenzyl-(2-dimethylaminoethyl)amino]-2-methoxy-pyrimidine (VIII) is shown to possess H1 receptor antagonist activity, with a potency similar to that observed for Tonzylamine. By contrast, a specific, although weak, antimuscarinic effect is displayed by 4-[benzyl-(2-dimethylaminoethyl)amino]-2-methoxy-5-methylthio-pyrimidine (XII).