1155847-27-0

Basic information

• Product Name: 1H-Pyrazolo[3,4-b]pyridine-3-acetic acid
• Synonyms: (1H-Pyrazolo[3,4-b]pyridin-3-yl)-acetic acid;1H-Pyrazolo[3,4-b]pyridine-3-acetic acid;2-(1H-Pyrazolo[3,4-b]pyridin-3-yl)acetic acid
• CAS NO: 1155847-27-0
• Molecular Formula: C8H7N3O2
• Molecular Weight: 177
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 1155847-27-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 413.9±47.0 °C(Predicted)
• Appearance: /
• Density: 1.56±0.1 g/cm3(Predicted)
• PKA: 2.43±0.10(Predicted)
• CAS DataBase Reference: 1H-Pyrazolo[3,4-b]pyridine-3-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-b]pyridine-3-acetic acid(1155847-27-0)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-b]pyridine-3-acetic acid(1155847-27-0)

Safety Data

• Hazardous Substances Data: 1155847-27-0(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1155847-27-0 differently. You can refer to the following data:
1. 1H-Pyrazolo[3,4-b]pyridine-3-acetic acid can act as intermediate used in the synthesis of certain aryloxy-, cycloalkyloxy-, and heterocyclyloxy- pyridines and pyrimidines that are potent HIV reverse transcriptase inhibitors useful in the treatment of H IV infection and AIDS.
2. Intermediate used in the synthesis of certain aryloxy-, cycloalkyloxy-, and heterocyclyloxy- pyridines and pyrimidines that are potent HIV reverse transcriptase inhibitors useful in the treatment of HIV infection and AIDS.

Upstream product

• 174180-76-8 3-bromomethylpyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester 
• 174180-77-9 tert-butyl 3-methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylate 
• 116834-96-9 3-methyl-1H-pyrazolo[3,4b]pyridine 
• 1155847-26-9 tert-butyl 3-(cyanomethyl)-1H-pyrazolo[3,4-b]pyridin-1-carboxylate 

Relevant articles and documents

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NITROGEN-CONTAINING FUSED RING COMPOUNDS AS CRTH2 ANTAGONISTS

The present application relates to nitrogen-containing fused ring compounds shown by general formula (I), a pharmaceutically acceptable salt thereof and a stereoisomer thereof as CRTH2 antagonist, wherein X1, X2, X3, X4, X5, W, X, Y, L1, L2, L3, A, B are as defined in the description; the present application further relates to a method for preparing the compounds, a pharmaceutical formulation and a pharmaceutical composition comprising the compounds, a use of the compounds for the manufacture of a medicament for the treatment and/or prevention of diseases related to activity of CRTH2.