1155878-40-2Relevant academic research and scientific papers
Synthesis of new α-Aryl-α-tetralones and α-Fluoro-α-aryl-α-tetralones, preliminary antiproliferative evaluation on drug resistant cell lines and in silico prediction of ADMETox properties
de Souza, Luana G.,Salustiano, Eduardo J.,da Costa, Kelli M.,Costa, Angela T.,Rumjanek, Vivian M.,Domingos, Jorge L.O.,Rennó, Magdalena N.,Costa, Paulo R.R.
, (2021/03/22)
α-aryl-α-tetralones and α-fluoro-α-aryl-α-tetralones derivatives were synthesized by palladium catalyzed α-arylation reaction of α-tetralones and α-fluoro-α-tetralones, with bromoarenes in moderate to good yields. These compounds were evaluated for their
Palladium-catalyzed direct α-arylation of α-fluoroketones: A straightforward route to α-fluoro-α-arylketones
Guo, Chen,Wang, Ruo-Wen,Guo, Yong,Qing, Feng-Ling
experimental part, p. 86 - 96 (2012/02/05)
The palladium-catalyzed direct α-arylation of both open-chain and cyclic α-fluoroketones by using P(o-tolyl)3 or RuPhos as ligand and K3PO4·3H2O as mild base has been developed. This method allows a variety of q
Pd-catalyzed arylation of silyl enol ethers of substituted α-fluoroketones
Guo, Yong,Twamley, Brendan,Shreeve, Jean'Ne M.
experimental part, p. 1716 - 1722 (2009/06/28)
α-Fluoro-α-aryl-ketones were synthesized by the Pd-catalyzed cross-coupling of aryl bromides with either α-fluoroketones or their corresponding silyl enol ethers. The direct arylation with an α-fluoroketone requires a strong base, such as potassium tert-b
