115646-37-2Relevant academic research and scientific papers
Glycerol derivatives, their production and use
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, (2008/06/13)
Compounds of the formula: STR1 wherein R1 is a higher alkyl group which may be substituted; R2 is a hydrogen, a lower alkyl group which may be substituted, a lower alkanoyl group which may be substituted or a lower alkylthiocarbamoyl group; R3 is a primary to tertiary amino group or a quaternary ammonium group; and n is 2 or 3, and salts thereof, have antitumor activity and platelet activating factor inhibitory activity.
Nitrogen- and sulfur-containing lipid compounds their production and use
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, (2008/06/13)
A compound of the general formula [I]: STR1 wherein R1 represents a higher alkyl group or an N-(higher alkyl)carbamoyl group, R2 represents a lower alkyl group, an acyl group having at least three carbon atoms, an N-(lower alkyl)carbamoyl group, an N-(lower alkyl)thiocarbamoyl group or a benzyl group, R represents a primary, secondary or tertiary amino group or a quaternary ammonium group, x is 1 or 2, y is a number of 0, 1 or 2, and z is an integer of 2-10, or a pharmaceutically acceptable salt thereof. The novel substances have both anti-tumor activity and platelet activating factor-inhibiting property, and they are effective as an anti-tumor agent without circulatory trouble.
