115654-61-0 Usage
General Description
(S)-N-BOC-LEUCINE-NITRILE is a chemical compound that belongs to the class of nitriles, which are organic compounds containing a cyano group (-C≡N). It is a derivative of leucine, an essential amino acid needed for protein synthesis and overall human health. The BOC (tert-butyloxycarbonyl) group is a protecting group often used in organic synthesis to temporarily mask reactive functional groups, such as amines, from unwanted reactions. (S)-N-BOC-LEUCINE-NITRILE has potential applications in medicinal chemistry and drug development, as it can serve as a building block for the synthesis of various pharmaceutical compounds. Additionally, its nitrile functionality makes it a valuable intermediate in the preparation of other nitrogen-containing organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 115654-61-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,6,5 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 115654-61:
(8*1)+(7*1)+(6*5)+(5*6)+(4*5)+(3*4)+(2*6)+(1*1)=120
120 % 10 = 0
So 115654-61-0 is a valid CAS Registry Number.
115654-61-0Relevant articles and documents
Photoinduced direct cyanation of C(sp3)-H bonds
Hoshikawa, Tamaki,Yoshioka, Shun,Kamijo, Shin,Inoue, Masayuki
, p. 874 - 887 (2013/05/09)
A general and practical synthetic protocol for the direct transformation of unreactive C(sp3)-H bonds to C(sp3)-CN bonds has been developed. The homolytic cleavage of the C-H bond is initiated by photo-excited benzophenone, and the resulting carbon radical subsequently reacts with tosyl cyanide to afford the corresponding nitrile in a highly efficient manner. The present methodology is widely applicable to various starting materials including ethers, alcohols, amine derivatives, alkanes, and alkylbenzenes. This newly developed C-H cyanation protocol provides a powerful tool for selective one-carbon elongation for the construction of architecturally complex molecules. Georg Thieme Verlag Stuttgart - New York.
