115694-82-1Relevant articles and documents
PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV
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Page/Page column 22; 23, (2017/01/09)
Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.
Stereoselective total synthesis of (-)-borrelidin
Vong, Binh G.,Kim, Sun Hee,Abraham, Sunny,Theodorakis, Emmanuel A.
, p. 3947 - 3951 (2007/10/03)
A convergent synthesis of (-)-borrelidin (1) is reported based on the retrosynthetic disconnections indicated in the picture. Highlights of the strategy include the construction of a strained enynone-containing macrolide and the installation of a cyano group in a regioselective manner by a novel molybdenum-catalyzed hydrostannation of the alkyne.