115709-68-7 Usage
Uses
Used in Pharmaceutical Research:
L-TRYPTOPHAN (INDOLE-2-13C) is used as a research reagent for the preparation of 13Cand 14C-labeled 5-benzyl and 5-indolylmethyl L-hydantoins. These labeled compounds are essential for studying the metabolic pathways and understanding the role of L-tryptophan in various biological processes.
Used in Metabolic Studies:
L-TRYPTOPHAN (INDOLE-2-13C) is used as a tracer molecule in metabolic studies to investigate the conversion of tryptophan into various neurotransmitters, such as serotonin, and other biologically active compounds. The 13C labeling allows researchers to track the metabolic fate of tryptophan and its derivatives in living organisms.
Used in Neurochemistry:
L-TRYPTOPHAN (INDOLE-2-13C) is used as a starting material for the synthesis of labeled neurotransmitters and other neurochemicals. These labeled compounds can be used to study the mechanisms of neurotransmission, neurodegenerative diseases, and the effects of drugs on the nervous system.
Used in Nutritional Research:
L-TRYPTOPHAN (INDOLE-2-13C) can be used as a labeled nutrient in nutritional research to study the absorption, metabolism, and utilization of tryptophan in the human body. This information can be valuable for developing dietary recommendations and understanding the role of tryptophan in overall health and well-being.
Used in Drug Development:
L-TRYPTOPHAN (INDOLE-2-13C) can be used in the development of new drugs targeting the metabolic pathways involving tryptophan. The labeled compound can help researchers identify potential drug candidates and optimize their pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 115709-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,7,0 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 115709-68:
(8*1)+(7*1)+(6*5)+(5*7)+(4*0)+(3*9)+(2*6)+(1*8)=127
127 % 10 = 7
So 115709-68-7 is a valid CAS Registry Number.
115709-68-7Relevant academic research and scientific papers
Synthesis of three isotopomers of L-tryptophan via a combination of organic synthesis and biotechnology
Berg, E. M. M. van den,Baldew, A. U.,Goede, A. T. J. W. de,Raap, J.,Lugtenburg, J.
, p. 73 - 81 (2007/10/02)
In this paper, we report the preparation of three isotopomers of L-tryptophan on a gram scale, specifically labelled with 99percent 15N (position 1) and 99percent 13C (position 2) in the indole ring; for position 3, the incorporation was 90percent 13C.The isotopically enriched indoles were synthesized from H(15)NO3, K(13)CN and (13)CH3CN and then converted, with L-serine, into the corresponding labelled L-tryptophans using genetic manipulated E. coli bacteria, which contain high amounts of the enzyme tryptophan synthetase.The 13C-13C, 13C-1H, 13C-15N and 15N-1H coupling constants of the indoles and the tryptophans were determined from the 1H NMR and 13C NMR spectra.
