115764-30-2Relevant academic research and scientific papers
Chemistry of O-Silylated Ketene Acetals: An Efficient Synthesis of Carbapenem and 1β-Methylcarbapenem Intermediates
Kita, Yasuyuki,Shibata, Norio,Tohjo, Takashi,Yoshida, Naoki
, p. 1795 - 1800 (2007/10/02)
3-(1-tert-Butyldimethylsiloxyethyl)-4-phenylsulfinylazetidin-2-one reacted smoothly with various types of O-silylated ketene acetals and silylated enol ethers in the presence of a catalytic amount of zinc iodide to give the corresponding trans-4-substitut
AN EXPEDITIOUS SYNTHESIS OF A 1Β-METHYLCARBAPENEM KEY INTERMEDIATE
Deziel, Robert,Endo, Masaki
, p. 61 - 64 (2007/10/02)
The β-methylcarbapenem key intermediate 4 was prepared via a novel aldol-type alkylation of 2 with the divalent tin enolate 6 generated in situ from 7 and metallic tin.
