1158486-96-4

Basic information

• Product Name: dimethyl α-hydroxy-3-fluorobenzylphosphonate
• Synonyms: dimethyl α-hydroxy-3-fluorobenzylphosphonate
• CAS NO: 1158486-96-4
• Molecular Weight: 234.164
• Mol File: 1158486-96-4.mol

Chemical Properties

• CAS DataBase Reference: dimethyl α-hydroxy-3-fluorobenzylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl α-hydroxy-3-fluorobenzylphosphonate(1158486-96-4)
• EPA Substance Registry System: dimethyl α-hydroxy-3-fluorobenzylphosphonate(1158486-96-4)

Safety Data

• Hazardous Substances Data: 1158486-96-4(Hazardous Substances Data)

Upstream product

• 868-85-9 Dimethyl phosphite 
• 456-48-4 3-Fluorobenzaldehyde 

Relevant articles and documents

Silica-Supported Tungstic Acid Catalyzed Synthesis and Antioxidant Activity of α-Hydroxyphosphonates

A green and efficient method has been accomplished for the synthesis of α-hydroxyphosphonates using silica-supported tungstic acid (STA) as a heterogeneous catalyst under solvent-free conditions at ambient temperature. The compounds obtained were characte

The preparation of dimethyl α-hydroxyphosphonates and the chemical shift non-equivalence of their diastereotopic methyl ester groups

Dimethyl α-hydroxyalkyl-, α-hydroxybenzyl-, α-hydroxyfurfuryl-, and α-hydroxy-α-thienylmethyl-phosphonates have been prepared in good yield by the alumina-catalyzed reaction of dimethyl phosphite with the corresponding alkanals, aryl aldehydes (or aryl methyl ketones), furfuraldehyde, and 2- or 3-thiophenecarboxaldehyde, respectively, thus confirming the general utility of this synthetic procedure. The 1H and 13C nmr spectra of the products exhibit characteristic chemical shift non-equivalence of the diastereotopic methyl ester groups, for which a tentative order of non-equivalence is reported and discussed. Copyright Taylor & Francis Group, LLC.