1158560-99-6 Usage
Uses
2-Chloro-N-[4-(1-cyanocyclopentyl)phenyl]-3-pyridinecarboxamide is an intermediate Apatinib 25-N-Oxide (A726160), a metabolite of the antiangiogenic agent and selective VEGFR2 inhibitor Apatinib (A726150).
Check Digit Verification of cas no
The CAS Registry Mumber 1158560-99-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,8,5,6 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1158560-99:
(9*1)+(8*1)+(7*5)+(6*8)+(5*5)+(4*6)+(3*0)+(2*9)+(1*9)=176
176 % 10 = 6
So 1158560-99-6 is a valid CAS Registry Number.
1158560-99-6Relevant articles and documents
Apatinib preparation method
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, (2017/04/28)
The present invention relates to an apatinib preparation method, wherein specifically an organic solvent is selected to perform refining crystallization to obtain the apatinib. The method of the present invention has advantages of simple operation and low cost, and is suitable for large-scale production.
