115869-49-3

Upstream product

• 107-86-8 3,3-dimethyl acrylaldehyde 
• 115869-38-0 (1-Methyl-4-oxo-3-phenyl-1,4-dihydro-quinolin-2-ylmethyl)-phosphonic acid dimethyl ester 
• 52343-38-1 dimethyl 2-oxo-3-phenylpropylphosphonate 
• 122-78-1 phenylacetaldehyde 
• 115869-34-6 dimethyl 2-hydroxy-3-phenylpropanephosphonate 

Relevant academic research and scientific papers

The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 20. Synthesis and Wittig Reactions of Dimethyl (4-Oxo-1,4-dihydro-Quinolin-2-yl)methanephosphonates

Isatoic anhydrides react with dilithiated 2-oxoalkanephosphonates to give dimethyl (4-oxo-1,4-dihydroquinolin-2-yl)methanephosphonates 5.These phosphonates undergo a Horner reaction with aldehydes to produce 2-(1-alkenyl)-4(1H)-quinolinones 10 in good yie