1158749-78-0 Usage
General Description
6-Benzyl-1,6-diazaspiro[3.4]octane is a chemical compound with a spirocyclic structure that contains a benzyl group attached to a diazaspiro ring system. It has potential pharmaceutical applications due to its ability to interact with certain biological targets, such as receptors in the central nervous system. The compound has been studied for its potential as a psychoactive drug, with effects similar to those of hallucinogenic substances. However, further research is needed to fully understand its pharmacological properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 1158749-78-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,8,7,4 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1158749-78:
(9*1)+(8*1)+(7*5)+(6*8)+(5*7)+(4*4)+(3*9)+(2*7)+(1*8)=200
200 % 10 = 0
So 1158749-78-0 is a valid CAS Registry Number.
1158749-78-0Relevant articles and documents
Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors
Sippy, Kevin B.,Anderson, David J.,Bunnelle, William H.,Hutchins, Charles W.,Schrimpf, Michael R.
scheme or table, p. 1682 - 1685 (2009/11/30)
Several N-pyridin-3-yl spirobicyclic diamines, designed as conformationally restricted analogs of tebanicline (ABT-594), were synthesized as novel ligands for nicotinic acetylcholine receptors (nAChR). The spirocyclic compounds exhibited weaker binding affinity, than other constrained analogs in accord with a pharmacophore model. Nevertheless, some (1a, 1b) possessed (partial) agonist potencies comparable to nicotine at the α4β2 subtype, but with greatly improved selectivity relative to the α3β4* nAChR.
