1158759-03-5

Basic information

• Product Name: 4-(Boc-aMinoMethyl)-4-Methylpiperidine hydrochloride
• Synonyms: 4-(Boc-aMinoMethyl)-4-Methylpiperidine hydrochloride;tert-butyl (4-methylpiperidin-4-yl)methylcarbamate;tert-butyl N-[(4-methylpiperidin-4-yl)methyl]carbamate;4-(Boc-aminomethyl)-4-methylpiperidine;4-(N-Boc-aminomethyl)4-pipecoline
• CAS NO: 1158759-03-5
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 264.7921
• Mol File: 1158759-03-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 325.7±15.0 °C(Predicted)
• Appearance: /
• Density: 0.964±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 12.72±0.46(Predicted)
• CAS DataBase Reference: 4-(Boc-aMinoMethyl)-4-Methylpiperidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Boc-aMinoMethyl)-4-Methylpiperidine hydrochloride(1158759-03-5)
• EPA Substance Registry System: 4-(Boc-aMinoMethyl)-4-Methylpiperidine hydrochloride(1158759-03-5)

Safety Data

• Hazardous Substances Data: 1158759-03-5(Hazardous Substances Data)

Usage

General Description

4-(Boc-aMinoMethyl)-4-Methylpiperidine hydrochloride is a chemical compound, a derivative of piperidine, notable for its use in pharmaceutical and chemical research. It often serves as a key building block in the synthesis of complex organic molecules. The term 'Boc' in its name refers to tert-butyloxycarbonyl, a complex organic compound used in the protection of amines in peptide synthesis. Meanwhile, hydrochloride denotes the presence of hydrochloric acid in the compound. Its exact properties, behavior and hazards may vary depending on detailed specifications.

Upstream product

• 1345728-57-5 1-benzyl-4-methylpiperidine-4-carboxamide 
• 1345728-53-1 1-(1-benzyl-4-methylpiperidin-4-yl)methylamine 
• 1345728-58-6 tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate 
• 948988-53-2 4-methylpiperidine-4-carbonitrile hydrochloride 
• 62718-32-5 1-benzyl-4-methyl-piperidine-4-carbonitrile 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Pyrimidine-4 (3H)-ketone heterocyclic compound, preparation method thereof and application of pyrimidine-4 (3H)-ketone heterocyclic compound in medicine

The invention relates to pyrimidine-4 (3H)-ketone heterocyclic compounds suitable for inhibiting or regulating SHP2, a preparation method of the pyrimidine-4 (3H)-ketone heterocyclic compounds and application of the pyrimidine-4 (3H)-ketone heterocyclic compounds in medicine. Specifically, the invention relates to a compound as shown in a general formula (I) and a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the compound or the pharmaceutically acceptable salt thereof, a method for treating and/or preventing related diseases mediated by SHP2, especially cancers by using the compound or the pharmaceutically acceptable salt thereof, and a preparation method of the compound or the pharmaceutically acceptable salt thereof. The invention also relates to application of the compound or the pharmaceutically acceptable salt thereof or a pharmaceutical composition containing the compound or the pharmaceutically acceptable salt thereof in preparation of drugs for treating and/or preventing SHP2-mediated related diseases. Wherein each substituent in the general formula (I) is as defined in the specification.

IMIDAZO[1,2-a]PYRIDINE DERIVATIVE

[Problem] To provide a compound useful as medicine having PDE4B inhibitory activity, in particular, as an active ingredient of a composition for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like. [Measures for Solution] The present inventors examined compounds having PDE4B inhibitory activity and found that a tricyclic or tetracyclic imidazo[1,2-a]pyridine derivative or salts thereof had a superior PDE4B inhibitory activity, thereby completing the present invention. The imidazo[1,2-a]pyridine derivative can be used as an agent for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like.