1158767-01-1

Basic information

• Product Name: (4,5,6,7-Tetrahydro-1H-indazol-5-yl)-carbaMic acid tert-butyl ester
• Synonyms: (4,5,6,7-Tetrahydro-1H-indazol-5-yl)-carbaMic acid tert-butyl ester;tert-butyl (4,5,6,7-tetrahydro-1H-indazol-5-yl)carbamate
• CAS NO: 1158767-01-1
• Molecular Formula: C₁₂H₁₉N₃O₂
• Molecular Weight: 237.29816
• Mol File: 1158767-01-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 432.2±34.0 °C(Predicted)
• Appearance: /
• Density: 1.16±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 12.13±0.20(Predicted)
• CAS DataBase Reference: (4,5,6,7-Tetrahydro-1H-indazol-5-yl)-carbaMic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5,6,7-Tetrahydro-1H-indazol-5-yl)-carbaMic acid tert-butyl ester(1158767-01-1)
• EPA Substance Registry System: (4,5,6,7-Tetrahydro-1H-indazol-5-yl)-carbaMic acid tert-butyl ester(1158767-01-1)

Safety Data

• Hazardous Substances Data: 1158767-01-1(Hazardous Substances Data)

Usage

General Description

The chemical compound (4,5,6,7-Tetrahydro-1H-indazol-5-yl)-carbaMic acid tert-butyl ester is a derivative of indazole, a heterocyclic compound with potential pharmaceutical applications. It is a carboxylic acid ester, specifically the tert-butyl ester, and contains a tetrahydroindazole group. (4,5,6,7-Tetrahydro-1H-indazol-5-yl)-carbaMic acid tert-butyl ester may be used in the synthesis of pharmaceuticals or as a research tool in the development of new drugs. Its structural features and potential pharmacological properties make it a molecule of interest in medicinal chemistry and drug discovery.

Upstream product

• 179321-49-4 N-(tert-butoxycarbonyl)-4-aminocyclohexanone 
• 1171130-67-8 (3-dimethylaminomethylene-4-oxo-cyclohexyl)-carbamic acid tert-butyl ester 

Downstream Products

• 955406-21-0 (3R,5R)-3-(2,6-dichloro-4-hydroxy-benzyl)-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955406-15-2 (3R,5S)-3-(4-hydroxy-2,6-dichloro-benzyl)-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955407-49-5 (3R,5R)-(+)-3-(3,5-dichloro-4'-fluoro-biphenyl-4-ylmethyl)-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955406-28-7 (3R,5S)-5-[3-(2,6-dichloro-4-hydroxy-benzyl)-2-oxo-pyrrolidin-1-yl]-4,5,6,7-tetrahydro-indazole-1-carboxylic acid tert-butyl ester 
• 955406-43-6 (3R,5S)-3-[2,6-dichloro-4-(morpholine-4-carbonyl)-benzyl]-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955407-50-8 (3R,5S)-3-[2,6-dichloro-4-(4-phenyl-piperidin-1-yl)-benzyl]-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955407-59-7 (3R,5S)-3-[2,6-dichloro-4-(4,4-difluoropiperidine-1-carbonyl)-benzyl]-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955407-57-5 (3R,5S)-3-[2,6-dichloro-4-(4-trifluoromethyl-piperidine-1-carbonyl)-benzyl]-1-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-2-one 
• 955406-23-2 (3R,5R)-trifluoro-methanesulfonic acid 3,5-dichloro-4-[2-oxo-1-(2-trifluoromethanesulfonyl-4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-3-ylmethyl]-phenyl ester 
• 955407-58-6 C₂₀H₁₇Cl₂F₆N₃O₆S₂ 
• 955406-17-4 (3R,5S)-trifluoro-methanesulfonic acid 3,5-dichloro-4-[2-oxo-1-(2-trifluoromethanesulfonyl-4,5,6,7-tetrahydro-2H-indazol-5-yl)-pyrrolidin-3-ylmethyl]-phenyl ester 
• 955406-56-1 C₂₀H₁₇Cl₂F₆N₃O₆S₂ 

Relevant articles and documents

CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1

The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compound