1158813-50-3Relevant academic research and scientific papers
QSAR analysis of pyrazolidine-3,5-diones derivatives as Dyrk1A inhibitors
Koo, Kyung Ah,Kim, Nam Doo,Chon, Yong Sog,Jung, Min-Su,Lee, Burm-Jong,Kim, Jung Ho,Song, Woo-Joo
, p. 2324 - 2328 (2009)
Individuals with Down syndrome (DS) suffer from mental retardation. Overexpression and the resulting increased specific activity of Dyrk1A kinase located on chromosome 21 cause a learning and memory deficit in Dyrk1A transgenic mice. To search for therape
