115883-85-7Relevant articles and documents
Synthesis, in vitro antioxidant activity, and physicochemical properties of novel 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives
Yüksek, Haydar,Koca, Ebru,Gürsoy-Kol, ?zlem,Akyildirim, Onur,?elebier, Mustafa
, p. 359 - 366 (2015)
In this study, eight new 3-alkyl(aryl)-4-[4-(4-methylbenzoxy)benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-one (4) compounds were synthesized by the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) with 4-(4-methylbenzoxy)benzaldehyde (1). The eight compounds were characterized using IR, 1H NMR, 13C NMR, and UV spectral data. In addition, the synthesized compounds were analyzed for their potential in vitro antioxidant activities, including reducing power, free radical scavenging and metal chelating activity. These antioxidant activities were compared to those from standard antioxidants, such as EDTA, BHA, BHT and α-tocopherol. Moreover, compounds 4 were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, tert-butyl alcohol, acetone and N,N-dimethylformamide). Thus, the half-neutralization potential values and the corresponding pKa values were determined in all cases. In addition, the lipophilicity of the synthesized compounds was investigated using HPLC. Kinetic parameters of the complexes were obtained for each stage of thermal degradation using the Coats-Redfern and Horowitz-Metzger methods.
Organic solvent controlling the oxidativity of potassium permanganate
Zheng, Min-Yan,Wei, Yong-Sheng,Fan, Guang,Huang, Yi
experimental part, p. 161 - 164 (2012/08/27)
It has been discovered that potassium permanganate can be a homogenous weak oxidant in organic solvent without the addition of water. If acetone is employed as the only solvent, among some common organic substrates included alkenes, alcohols, arenes, aldehydes and phenols, secondary alcohols are converted to the corresponding ketones and aldehydes to the corresponding acid. Compared with oxidation reaction of potassium permanganate in water, in anhydrous acetone system, potassium permanganate as a weaker oxidant has no influence on the alkyls in benzene rings, double bonds and so on. So potassium permanganate can exhibit selectivity by solvent controlling. Especially, when aldehydes are oxidized, the oxidation process is a green organic reaction for nearly all coproducts and solvent can be recycled.
Effects of Branching of the Ester Alkyl Chain on the Mesomorphic Properties of Alkyl 4-benzoates
Matsuzaki, Hiroyuki,Matsunaga, Yoshio
, p. 2300 - 2305 (2007/10/02)
The mesomorphic properties of five homologous series of alkyl 4-benzoates, where X=CN, NO2, CH3, Cl, and CH3COO, have been studied.The ester alkyl groups employed were the following eleven types: ethyl and p