115891-14-0 Usage
Nicotine acid derivative
2-[2-(Dimethylamino)ethyl]aminonicotinic acid is a compound that contains a nicotinic acid core, which is a form of Vitamin B3.
Amino groups
The compound is made up of a nicotinic acid molecule with two ethylenediamine groups attached to it, which contain amino groups.
Strong base
The compound is a strong base with a pKa value of 8.5 for the amino groups.
Organic synthesis
Due to its strong basicity, it is useful in organic synthesis.
Chelating agent
It is commonly used as a chelating agent for metal ions.
Ligand
The compound can also act as a ligand for coordination complexes.
Medical applications
It has potential applications in the field of medicine, due to its ability to modify the pharmacokinetic properties of drugs and improve their solubility.
Check Digit Verification of cas no
The CAS Registry Mumber 115891-14-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,8,9 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 115891-14:
(8*1)+(7*1)+(6*5)+(5*8)+(4*9)+(3*1)+(2*1)+(1*4)=130
130 % 10 = 0
So 115891-14-0 is a valid CAS Registry Number.
115891-14-0Relevant articles and documents
Antiallergy Agents. 1. Substituted 1,8-Naphthyridin-2(1H)-ones as Inhibitors of SRS-A Release
Sherlock, Margaret H.,Kaminski, James J.,Tom, Wing C.,Lee, Joe F.,Wong, Shing-Chun,et al.
, p. 2108 - 2121 (2007/10/02)
A novel class of antiallergy agents, the substituted 1,8-naphthyridin-2(1H)-ones, is described.The present compounds are orally active, potent inhibitors of allergic and nonallergic bronchospasm in animal models.Structure-activity studies of the lead compound in this sereis, 1-phenyl-3-n-butyl-4-hydroxynaphthyridin-2(1H)-one (11), identified three compounds of interest, 1-phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (12), 1-(3'-chlorophenyl)-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (87), and 1-(3'-methoxyphenyl)-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (89).The mechanism of antiallergy activity may involve inhibition of the release of the sulfidopeptide leukotrienes. 1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one, Sch 33303 (12), was selected for preclinical development as an antiallergy agent.
