1158956-76-3Relevant academic research and scientific papers
Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor α and β agonists
Poutiainen, Pekka K.,Ven?l?inen, Tuomas A.,Per?kyl?, Mikael,Matilainen, Juha M.,V?is?nen, Sami,Honkakoski, Paavo,Laatikainen, Reino,Pulkkinen, Juha T.
experimental part, p. 3437 - 3447 (2010/10/03)
In this work, 52 diphenyl-4,5-dihydroisoxazoles and -3-hydroxy ketones were prepared and their estrogen receptor α (ERα) and estrogen receptor β (ERβ) activities were explored in order to systematize and maximize their biological activity. The biological
NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY
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Page/Page column 26, (2009/06/27)
This invention relates to β-hydroxyketones and β-alkoxyketones of formula (I), to their use as estrogen receptor modulators, and to methods for their preparation.
