115898-57-2Relevant academic research and scientific papers
Aryl substituted nitrogen heterocyclic antidepressants
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, (2008/06/13)
Antidepressant agents having the formula STR1 wherein R1 is a polycycloalkyl group; R2 is methyl or ethyl, X is O; and Y comprises a 5-membered heterocyclic ring having one or two nitrogens.
Calcium-independent phosphodiesterase inhibitors as putative antidepressants: [3-(bicycloalkyloxy)-4-methoxyphenyl]-2-imidazolidinones
Saccomano,Vinick,Koe,Nielsen,Whalen,Meltz,Phillips,Thadieo,Jung,Chapin,Lebel,Russo,Helweg,Johnson Jr.,Ives,Williams
, p. 291 - 298 (2007/10/02)
The synthesis and biological properties of a novel series of selective calcium-independent phosphodiesterase inhibitors are described. These compounds also inhibit the specific binding of [3H]rolipram to rat brain membranes and exhibit efficacy
