1158985-17-1 Usage
Description
(S)-3-aminoheptan-1-ol, also known as L-norleucine, is an organic compound characterized by its chemical formula C7H17NO. It is an amino alcohol, featuring both an amino group and a hydroxyl group. As a chiral molecule, it has a single chiral center, leading to the existence of two enantiomers: (S)-3-aminoheptan-1-ol and (R)-3-aminoheptan-1-ol. (S)-3-aminoheptan-1-ol is predominantly utilized in the synthesis of pharmaceuticals and serves as a chiral building block in various organic chemistry reactions.
Uses
Used in Pharmaceutical Synthesis:
(S)-3-aminoheptan-1-ol is used as a starting material for the preparation of various pharmaceutical compounds. Its unique structure and chirality make it a valuable component in the development of new drugs with specific therapeutic properties.
Used as a Chiral Building Block:
In the field of organic chemistry, (S)-3-aminoheptan-1-ol is employed as a chiral building block for the synthesis of complex organic molecules. Its presence can influence the stereochemistry of the final product, which is crucial for the biological activity and selectivity of the synthesized compounds.
Used in Asymmetric Catalysis:
(S)-3-aminoheptan-1-ol is used as a precursor in the production of chiral ligands for asymmetric catalysis. These ligands are essential for enantioselective reactions, where the synthesis of one enantiomer is favored over the other, leading to more efficient and selective chemical processes.
Used in Medicinal Research:
Due to its biological activity, (S)-3-aminoheptan-1-ol is being studied for its potential therapeutic uses in medicine. Its unique properties and interactions with biological systems may lead to the discovery of new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1158985-17-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,8,9,8 and 5 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1158985-17:
(9*1)+(8*1)+(7*5)+(6*8)+(5*9)+(4*8)+(3*5)+(2*1)+(1*7)=201
201 % 10 = 1
So 1158985-17-1 is a valid CAS Registry Number.
1158985-17-1Relevant articles and documents
PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS
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, (2019/12/15)
The present disclosure relates to a class of pyrimidine derivatives having immunomodulating properties that act via TLR7 which are useful in the treatment of lung cancer and other respiratory conditions.
Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus
McGowan, David,Herschke, Florence,Pauwels, Frederik,Stoops, Bart,Last, Stefaan,Pieters, Serge,Scholliers, Annick,Thoné, Tine,Van Schoubroeck, Bertrand,De Pooter, Dorien,Mostmans, Wendy,Khamlichi, Mourad Daoubi,Embrechts, Werner,Dhuyvetter, Deborah,Smyej, Ilham,Arnoult, Eric,Demin, Samu?l,Borghys, Herman,Fanning, Gregory,Vlach, Jaromir,Raboisson, Pierre
, p. 7936 - 7949 (2016/11/07)
Toll-like receptor (TLR) 7 and 8 agonists can potentially be used in the treatment of viral infections and are particularly promising for chronic hepatitis B virus (HBV) infection. An internal screening effort identified a pyrimidine Toll-like receptor 7 and 8 dual agonist. This provided a novel alternative over the previously reported adenine and pteridone type of agonists. Structure-activity relationship, lead optimization, in silico docking, pharmacokinetics, and demonstration of ex vivo and in vivo cytokine production of the lead compound are presented.
QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES
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, (2014/03/25)
This invention relates to quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy of disorders in which the modulation of toll-like-receptors is involved.
