1158997-68-2Relevant academic research and scientific papers
Iron-catalyzed direct sulfenylation and selenylations of phenylpyrazoles: Synthesis of fipronil derivatives with disulfides promoted by a catalytic amount of iodine
Xu, Mei,Zhang, Xiao Hong,Zhong, Ping
, p. 3472 - 3481 (2012)
The direct thiolation of phenylpyrazole with disulfide using the FeBr 3/I2 complex as the catalyst in MeCN at 80 °C was reported. With the optimum conditions, several fipronil derivatives of 4-sulfenylpyrazole were synthesized by the reaction of 5-amino-1-[2,6-dichloro- 4-(trifluoromethyl)phenyl-lH-pyrazole-3-arbonitrile (1a) with disulfides (2) in moderate to good yields. The coupling reaction with diaryl diselane also occurred under similar conditions.
Substrate-Controlled [5+1] Annulation of 5-Amino-1H-phenylpyrazoles with Alkenes: Divergent Synthesis of Multisubstituted 4,5-Dihydropyrazolo[1,5-a]quinazolines
Jiang, Xunyuan,Wei, Xiaoyi,Lin, Fei,Zhang, Zhixiang,Yao, Guangkai,Yang, Shuai,Zhao, Weijing,Zhao, Chen,Xu, Hanhong
supporting information, p. 3997 - 4003 (2020/06/17)
A new and efficient [5+1] annulation reaction for the first synthesis of 5,5-disubstituted 4,5-dihydropyrazolo[1,5-a]quinazolines is described. This transition-metal-free tandem cyclization was performed with 5-amino-1H-phenylpyrazole and readily availabl
