1159000-88-0 Usage
General Description
5-Bromo-2-(4-methoxybenzyloxy)pyrimidine is a chemical compound with the molecular formula C12H10BrN2O2. It is a pyrimidine derivative with a bromine atom at the 5th position and a 4-methoxybenzyloxy group attached to the 2nd position. 5-Bromo-2-(4-methoxybenzyloxy)pyrimidine has potential applications in medical and pharmaceutical research due to its ability to interact with biological targets such as enzymes and receptors. It can be used as a building block in the synthesis of various pharmaceutical compounds, as well as in the development of new drug candidates. Additionally, its unique structure and properties make it a valuable tool in the study of biochemical processes and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 1159000-88-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,9,0,0 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1159000-88:
(9*1)+(8*1)+(7*5)+(6*9)+(5*0)+(4*0)+(3*0)+(2*8)+(1*8)=130
130 % 10 = 0
So 1159000-88-0 is a valid CAS Registry Number.
1159000-88-0Relevant articles and documents
Synthesis and cytotoxic evaluation for some new 2,5-disubstituted pyrimidine derivatives for anticancer activity
Reddy, Onteddu Surendranatha,Suryanarayana, Ch. Venkata,Narayana,Anuradha,Babu, B. Hari
, p. 1777 - 1788 (2015)
Abstract An efficient synthetic approach for 2,5-disubstituted pyrimidines has been reported. The desired 2,5-substituted pyrimidines were obtained by Suzuki coupling of 2-substituted benzyloxy-5-bromopyrimidines with various aryl boronic acids in the presence catalytic amount of PdCl2(PPh3)2 with 0.5 M aqueous Na2CO3 in water at 80 °C. 2-Benzyloxy-5-bromopyrimidines were synthesized, in turn by the reaction of 2-chloro-5-bromopyrimidine with substituted benzyl alcohols in the presence of Cs2CO3 in CH3CN:DMF (1:1). Some of the 2,5-disubstituted pyrimidines have shown moderate in vitro cytotoxic activity against HeLa cell line.
