1159010-94-2

Usage

Uses

Used in Pharmaceutical Industry:
6-Hydroxy-5-Methylpyrimidine-4-carboxylic acid is used as a pharmaceutical intermediate for the synthesis of various biologically active compounds due to its unique structural features, which can be further modified to create new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
6-Hydroxy-5-Methylpyrimidine-4-carboxylic acid is used as a building block in chemical synthesis for creating a range of organic compounds, leveraging its reactive functional groups to form diverse molecular structures with specific properties for various applications in the chemical and materials science fields.

Upstream product

• 759-65-9 diethyl oxalpropionate 
• 593-87-3 guanidine acetic acid 
• 3473-63-0 formamidine acetic acid 

Downstream Products

• 1350745-52-6 C₂₄H₂₉F₃N₄O₄ 
• 1350745-53-7 C₂₈H₄₀N₄O₄ 
• 1416328-86-3 C₃₁H₄₀F₃N₅O₄ 
• 1312780-00-9 C₁₉H₂₃N₃O₃ 
• 1349114-87-9 C₁₂H₉Cl₂N₃O₂ 
• 1349114-62-0 C₁₃H₁₀F₃N₃O₂ 
• 1349114-61-9 C₁₅H₁₃ClF₃N₃O₂ 
• 1349114-46-0 C₁₅H₁₄F₃N₃O₂ 
• 1349113-00-3 C₂₄H₃₀F₃N₅O₃ 
• 1349197-77-8 C₁₆H₁₆F₃N₃O₃ 
• 1349197-78-9 C₂₀H₂₄F₃N₃O₃ 
• 1349197-44-9 C₃₃H₃₆F₃N₅O₃ 
• 933702-12-6 C₆H₅ClN₂O₂ 
• 1312779-99-9 C₂₁H₂₇N₃O₃ 

Relevant academic research and scientific papers

NEW SELECTIVE CCR2 ANTAGONISTS

The present invention relates to novel and selective antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD as well as pain.

NEW CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.

NEW SELECTIVE CCR2 ANTAGONISTS

The present invention relates to novel and selective antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD as well as pain.

NEW CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) of Formula (I) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.

NOVEL CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) of formula (I) wherein HET is a group selected from among formulas (IIa) (IIb) (IIc) (IId) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD and pain diseases.

NEW CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD and pain diseases

CCR2 ANTAGONISTS AND USES THEREOF

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.

CYCLIC PYRIMIDIN-4-CARBOXAMIDES AS CCR2 RECEPTOR ANTAGONISTS FOR TREATMENT OF INFLAMMATION, ASTHMA AND COPD

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD. Formula (I), wherein A is selected from among a single bond, =CH-, -CH2-, -O-, -S-, and -NH-; wherein n is 1, 2 or 3; wherein Z is C or N, the other variables are as defined in the claims, as well as in form of their acid addition salts with pharmacologically acceptable acids.