1159099-79-2Relevant academic research and scientific papers
Synthesis and biological evaluation of potent glycosidase inhibitors: 4-deoxy-4,4-difluoroisofagomine and analogues
Li, Rui-jie,Bols, Mikael,Rousseau, Cyril,Zhang, Xin-gang,Wang, Ruo-wen,Qing, Feng-Ling
experimental part, p. 3717 - 3727 (2009/09/30)
A series of 4,4-difluoroisofagomine analogues were synthesized. These compounds were tested for inhibition of eight glycosidases. The 3R,5R isomer 1 is a new and potent inhibitor against β-glucosidase from almonds with Ki value of 1.2 μM. The i
