115914-38-0

Basic information

• Product Name: dimethyl 3-(2,4,6-trimethoxyphenyl)isoxazole-4,5-dicarboxylate
• Synonyms: dimethyl 3-(2,4,6-trimethoxyphenyl)isoxazole-4,5-dicarboxylate
• CAS NO: 115914-38-0
• Molecular Formula: C₁₆H₁₇NO₈
• Molecular Weight: 351.30808
• Mol File: 115914-38-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: dimethyl 3-(2,4,6-trimethoxyphenyl)isoxazole-4,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 3-(2,4,6-trimethoxyphenyl)isoxazole-4,5-dicarboxylate(115914-38-0)
• EPA Substance Registry System: dimethyl 3-(2,4,6-trimethoxyphenyl)isoxazole-4,5-dicarboxylate(115914-38-0)

Safety Data

• Hazardous Substances Data: 115914-38-0(Hazardous Substances Data)

Upstream product

• 2904-59-8 2,4,6-trimethoxybenzonitrile N-oxide 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 51903-38-9 2,4,6-trimethoxybenzaldehyde oxime 
• 830-79-5 2,4,6-trimethoxybenzaldehyde 

Downstream Products

• 115914-40-4 3-(2,4,6-Trimethoxyphenyl)-4,5-isoxazoledicarboxylic acid 

Relevant articles and documents

Synthesis, Characterization, Antimicrobial and Antioxidant Activities of 1,2,4-triazolyl-isoxazole Moieties via Dehydration Reactions of Carbohy-drazides

For the reason of distinct place in the field of medicinal? and pharmaceutical chemistry of 1,2,4-triazole derivatives, a new class of fused 1,2,4-triazolyl-isoxazole moieties was prepared from 3-(2,4,6-trimethoxyphenyl)isoxazolo-4,5-bis[carbonyl-(4?-phenyl) thiosemicarbazide via dehydration reactions of carbohydrazides by using the appropriate chemical reagents. The structures of the compounds were elucidated by both elemental and spectral (IR, NMR and MS) analyses. The in vitro anti-oxidant activity of the new compounds was determined by free radical scavenging and metal chelating activity. All the synthesized compounds showed good activity according to free radical scavenging and metal chelating activity compared with standards. The new compounds were screened in vitro antibac-terial activity against three gram-positive bacteria and three gram-negative bacteria.