115923-75-6

Basic information

• Product Name: Acetic acid (4S,5S)-5-fluoro-1-methyl-2,6-dioxo-hexahydro-pyrimidin-4-yl ester
• CAS NO: 115923-75-6
• Molecular Weight: 204.158
• Mol File: 115923-75-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (4S,5S)-5-fluoro-1-methyl-2,6-dioxo-hexahydro-pyrimidin-4-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (4S,5S)-5-fluoro-1-methyl-2,6-dioxo-hexahydro-pyrimidin-4-yl ester(115923-75-6)
• EPA Substance Registry System: Acetic acid (4S,5S)-5-fluoro-1-methyl-2,6-dioxo-hexahydro-pyrimidin-4-yl ester(115923-75-6)

Safety Data

• Hazardous Substances Data: 115923-75-6(Hazardous Substances Data)

Upstream product

• 608-34-4 3-methyluracil 
• 78948-09-1 acetyl hypofluorite 

Downstream Products

• 4840-69-1 5-fluoro-3-methyl-1H-pyrimidine-2,4-dione 

Relevant articles and documents

Glorination of Pyrimidines. Part 2. Mechanistic Aspects of the Reaction of Acetyl Hypofluorite with Uracil and Cytosine Derivatives

The reaction of acetyl hypofluorite (AcOF) with uracil, cytosine, and some N-1-substituted derivatives dissolved in either acetic acid or water has been investigated.Analysis by radio-h.p.l.c., using (18)f as a tracer, and by (1)H n.m.r. revealed that a substituent at N-1 of uracil has a remarkable effect on the stability of the intermediate 6-acetoxy-5-fluoro-5,6-dihydrouracils.In addition, it was found that these cytosine adducts rapidly deaminate in water yielding their corresponding uracil analogues.