115923-86-9 Usage
Molecular Structure
The chemical has a pyrimidine ring structure with a cis configuration.
Fluorine Atom
The chemical has a fluorine atom at position 5 of the pyrimidine ring.
Hydroxyl Group
The chemical has a hydroxyl group at position 6 of the pyrimidine ring.
Amino Group
The chemical has an amino group at position 4 of the pyrimidine ring.
Methyl Group
The chemical has a methyl group at position 1 of the pyrimidine ring.
Use as Intermediate
The chemical is commonly used as an intermediate in the synthesis of pharmaceuticals.
Production of Antiviral Drugs
The chemical is particularly used in the production of antiviral drugs.
Importance of Cis Configuration
The cis configuration of the chemical is important for its biological activity as it can influence the interactions of the molecule with other biomolecules.
Check Digit Verification of cas no
The CAS Registry Mumber 115923-86-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,9,2 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 115923-86:
(8*1)+(7*1)+(6*5)+(5*9)+(4*2)+(3*3)+(2*8)+(1*6)=129
129 % 10 = 9
So 115923-86-9 is a valid CAS Registry Number.
115923-86-9Relevant articles and documents
Glorination of Pyrimidines. Part 2. Mechanistic Aspects of the Reaction of Acetyl Hypofluorite with Uracil and Cytosine Derivatives
Visser, W. M. Gerard,Herder, E. Renella,Kanter, Frans J. J. de,Herscheid D. M. Jacobus
, p. 1203 - 1208 (2007/10/02)
The reaction of acetyl hypofluorite (AcOF) with uracil, cytosine, and some N-1-substituted derivatives dissolved in either acetic acid or water has been investigated.Analysis by radio-h.p.l.c., using (18)f as a tracer, and by (1)H n.m.r. revealed that a substituent at N-1 of uracil has a remarkable effect on the stability of the intermediate 6-acetoxy-5-fluoro-5,6-dihydrouracils.In addition, it was found that these cytosine adducts rapidly deaminate in water yielding their corresponding uracil analogues.