1159266-86-0

Basic information

• Product Name: C₂₈H₃₈N₂O₅
• CAS NO: 1159266-86-0
• Molecular Weight: 482.62
• Mol File: 1159266-86-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₈N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₈N₂O₅(1159266-86-0)
• EPA Substance Registry System: C₂₈H₃₈N₂O₅(1159266-86-0)

Safety Data

• Hazardous Substances Data: 1159266-86-0(Hazardous Substances Data)

Upstream product

• 78603-97-1 (S)-2-amino-1,1-diphenyl-4-methylpentan-1-ol 
• 161979-36-8 (4S,5R)-N-t-butoxycarbonyl-5-methyl-1,3-oxazolidine-4-carboxylic acid 

Downstream Products

• 1159266-78-0 (4S,5R)-N-((S)-1-hydroxy-4-methyl-1,1-diphenylpentan-2-yl)-5-methyloxazolidine-4-carboxamide 

Relevant articles and documents

Highly efficient small organic molecules for enantioselective direct aldol reaction in organic and aqueous media

(Chemical Equation Presented) A series of highly efficient organocatalysts have been derived from naturally available amino acids for carrying out enantioselective direct aldol reaction in both organic and aqueous medium. The aldol products were obtained in high diastereoselectivities (up to 99:1) and enantioselectivities (up to >99% ee) for a broader range of substrates using 1 mol % of a catalyst. The results demonstrate that the structural features of organocatalysts play a crucial role in obtaining high optical purity of aldol adducts in an aqueous medium. Further, the role of water in increasing the rate and enantioselectivity of the reaction has been illustrated. Moreover, the aldol products have been employed in the synthesis of chiral amino alcohols which act as useful intermediates for building up complex natural products.