115936-46-4Relevant academic research and scientific papers
Polyhydroxy amino acid derivatives via β-lactams using enantiospecific approaches and microwave techniques
Bose, Ajay K.,Banik, Bimal K.,Mathur, Chandra,Wagle, Dilip R.,Manhas, Maghar S.
, p. 5603 - 5619 (2007/10/03)
Enantiospecific synthesis has been developed for α-hydroxy β-lactams of predictable absolute configuration starting with readily available carbohydrates. Stereospecific approaches and microwave assisted chemical reactions have been utilized for the prepar
Synthesis of novel 4-(5'-pyrrolidinyl)-β-lactams
Grigg, Ronald,Thornton-Pett, Mark,Xu, Juan,Xu, Long-He
, p. 13841 - 13866 (2007/10/03)
The synthesis of novel 4-(5'-pyrrolidinyl)-β-lactams from imines derived from 4-formyl-β-lactams and α-amino esters via cascade imine → azomethine ylide → 1,3-dipolar cycloaddition reactions is described. These cascades are endo-specific, exhibit facial stereoselectivity and occur in good to excellent yields.
Studies on Lactams. 81. Enantiospecific Synthesis and Absolute Configuration of Substituted β-Lactams from D-Glyceraldehyde Acetonide
Wagle, Dilip R.,Garai, Chandra,Chiang, Julian,Monteleone, Michael G.,Kurys, Barbara E.,et al.
, p. 4227 - 4236 (2007/10/02)
Optically active 3,4-disubstituted 2-azetidinones have been prepared in good yield by the annelation of Schiff bases from D-glyceraldehyde acetonide with acid chlorides (or equivalent) and triethylamine.The utility of this enantiospecific synthesis was ex
