115944-89-3Relevant academic research and scientific papers
SYNTHETIC STUDIES ON TETRODOTOXIN (1) STEREOCONTROLLED SYNTHESIS OF THE CYCLOHEXANE MOIETY
Isobe, Minoru,Nishikawa, Toshio,Pikul, Stanislaw,Goto, Toshio
, p. 6485 - 6488 (2007/10/02)
Tetrodotoxin is a potent neurotoxin, for which we planned a chemical synthesis in the optically active form.The key steps are i) Diels-Alder cycloaddition to form the optically active system with the cyclohexane moiety, ii) introduction of one-carbon frag
