1159573-88-2Relevant academic research and scientific papers
PROCESSES FOR PREPARATION OF POLYMORPHIC FORMS OF LACOSAMIDE
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Page/Page column 12-13, (2011/06/19)
The present invention relates to processes for the preparation of crystalline polymorphic forms of lacosamide (Formula I), including processes for inter-conversion among such polymorphic forms.
PROCESSES FOR REDUCING IMPURITIES IN LACOSAMIDE
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Page/Page column 13-14, (2011/08/21)
The present invention relates to processes for reducing impurities in lacosamide during the preparation of lacosamide. The invention provides processes for minimizing or removing impurities such as (2R)-2-(acetylamino)-3-(benzylamino)-3-oxopropyl acetate of Formula II or (2R)-2-propanoylamino-N-benzyl-3-methoxypropionamide of Formula III in lacosamide.
Intermediate compounds and their use in preparation of lacosamide
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Page/Page column 15, (2009/06/27)
The present invention is concerned with novel compounds and their use for the preparation of lacosamide. The present invention also contemplates processes for the preparation of lacosamide employing the novel compound of general Formula II, Formula IIa or Formula IIb as intermediate. Wherein R1 is -OH or -OMe; R2 is -OH or -NH-CH2-C6H5.
INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE
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Page/Page column 8, (2009/06/27)
The present invention is concerned with novel compounds and their use for the preparation of lacosamide. The present invention also contemplates processes for the preparation of lacosamide employing the novel compound of general Formula II, Formula IIa or Formula IIb as intermediate. Wherein R1 is —OH or —OMe;R2 is —OH or —NH—CH2—C6H5.
