1159601-85-0

Basic information

• Product Name: 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(1-methyl-1H-pyrazol-4-yl)-nicotinamide
• Synonyms: 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(1-methyl-1H-pyrazol-4-yl)-nicotinamide
• CAS NO: 1159601-85-0
• Molecular Weight: 389.414
• Mol File: 1159601-85-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(1-methyl-1H-pyrazol-4-yl)-nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(1-methyl-1H-pyrazol-4-yl)-nicotinamide(1159601-85-0)
• EPA Substance Registry System: 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-N-(1-methyl-1H-pyrazol-4-yl)-nicotinamide(1159601-85-0)

Safety Data

• Hazardous Substances Data: 1159601-85-0(Hazardous Substances Data)

Upstream product

• 1159599-10-6 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid 
• 69843-13-6 1-methyl-4-aminopyrazole 
• 1159599-08-2 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester 
• 73781-91-6 6-Chloronicotinic acid methyl ester 
• 18718-79-1 5-methyl-3-phenyl-4-isoxazolylmethanol 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF ISOXAZOLYL- METHOXY NICOTINIC ACIDS

The present invention relates to a process for the preparation of a compound of formula (I) wherein R1 and R2 are as defined herein, which is useful as an intermediate in the preparation of active pharmaceutical compounds.

ISOXAZOLE-PYRIDINE DERIVATIVES

The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and useful for the treatment of cognitive disorders, such as Alzheimer's disease.