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CAS

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115964-29-9

Tosufloxacin tosylate, also known as Ozex or Tosuxacin, is a fluoroquinolone antibacterial agent structurally related to temafloxacin. It functions as a microbial DNA topoisomerase inhibitor, making it effective against beta-lactamase producing organisms. Tosufloxacin tosylate is particularly noted for its efficacy against Salmonella enteritidis and is characterized by its white to off-white solid appearance.

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  • 115964-29-9 Structure

  • Basic information

    1. Product Name: Tosufloxacin tosylate
    2. Synonyms: TOSUFLOXACIN TOSYLATE;1,8-naphthyridine-3-carboxylicacid,7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluoro;4-dihydro-4-oxo-phenyl)-6-fluoro-mono(4-methylbenzenesulfonate);a64730;t3262;1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, mono(4-methylbenzenesulfonate) (9CI);Tosuxacin;7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate
    3. CAS NO:115964-29-9
    4. Molecular Formula: C26H23F3N4O6S
    5. Molecular Weight: 576.54
    6. EINECS: N/A
    7. Product Categories: Antibiotics for Research and Experimental Use;Biochemistry;Quinolones (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 115964-29-9.mol

  • Chemical Properties

    1. Melting Point: 251-252°C
    2. Boiling Point: 614.4 °C at 760 mmHg
    3. Flash Point: 325.4 °C
    4. Appearance: White to off-white solid
    5. Density: 1.558g/cm3
    6. Vapor Pressure: 5.96E-16mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: Refrigerator
    9. Solubility: DMSO (Slightly), Methanol (Slightly)
    10. BRN: 7617816
    11. CAS DataBase Reference: Tosufloxacin tosylate(CAS DataBase Reference)
    12. NIST Chemistry Reference: Tosufloxacin tosylate(115964-29-9)
    13. EPA Substance Registry System: Tosufloxacin tosylate(115964-29-9)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS: QN2791000
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 115964-29-9(Hazardous Substances Data)

115964-29-9 Usage

Uses

Used in Pharmaceutical Industry:
Tosufloxacin tosylate is used as a therapeutic antimicrobial for the treatment of respiratory infections. It is particularly effective against Salmonella enteritidis, making it a valuable addition to the arsenal of antibiotics used to combat bacterial infections in the respiratory system.
Used in Antimicrobial Treatments:
Tosufloxacin tosylate is utilized as an antimicrobial agent in the treatment of various respiratory infections. Its ability to inhibit microbial DNA topoisomerase and target beta-lactamase producing organisms contributes to its effectiveness in combating a range of bacterial infections, particularly those caused by Salmonella enteritidis.

Originator

Toyama (Japan)

Check Digit Verification of cas no

The CAS Registry Mumber 115964-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,9,6 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 115964-29:
(8*1)+(7*1)+(6*5)+(5*9)+(4*6)+(3*4)+(2*2)+(1*9)=139
139 % 10 = 9
So 115964-29-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H15F3N4O3.C7H8O3S.H2O/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25;1-6-2-4-7(5-3-6)11(8,9)10;/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29);2-5H,1H3,(H,8,9,10);1H2

115964-29-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Tosufloxacin tosylate

1.2 Other means of identification

Product number -
Other names Tosuxacin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:115964-29-9 SDS

115964-29-9Downstream Products

115964-29-9Relevant articles and documents

Preparation method of tosufloxacin tosylate monohydrate

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Paragraph 0024-0027, (2019/08/02)

The invention provides a preparation method of tosufloxacin tosylate monohydrate, the method uses 7-(3-aminopyrrolidine-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8] naphthyridine-3-carboxylic acid ethyl ester as a tosufloxacin tosylate sy

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