115981-96-9Relevant articles and documents
Effects of Addition of a 2-Methyl Group to Ethyl Nipecotates (β-Meperidines) on Receptor Affinities and Opiate Agonist/Antagonist Activities
Lawson, John A.,Cheng, Alice,DeGraw, Joseph,Frenking, Gernot,Uyeno, Edward,et al.
, p. 2015 - 2021 (2007/10/02)
A series of 2-methyl-3-carbethoxy-3-(m-hydroxyphenyl)piperidine opiates (13a-d) with N-substituent variations have been synthesized, and their receptor affinities and in vivo agonist and antagonist activities and energy-conformational profiles have been d