1159883-72-3Relevant academic research and scientific papers
Imidazo[2,1-b]thiazoles: Multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases
Fidanze, Steve D.,Erickson, Scott A.,Wang, Gary T.,Mantei, Robert,Clark, Richard F.,Sorensen, Bryan K.,Bamaung, Nwe Y.,Kovar, Peter,Johnson, Eric F.,Swinger, Kerren K.,Stewart, Kent D.,Zhang, Qian,Tucker, Lora A.,Pappano, William N.,Wilsbacher, Julie L.,Wang, Jieyi,Sheppard, George S.,Bell, Randy L.,Davidsen, Steven K.,Hubbard, Robert D.
scheme or table, p. 2452 - 2455 (2010/07/16)
The design and enzyme activities of a novel class of imidazo[2,1-b]thiazoles is presented.
IMIDAZO-THIAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS
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Page/Page column 84, (2009/07/03)
Compounds of formula I that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed. Formula I and therapeutically acceptable salts, prodrugs and salts of prodrugs thereof, wherein X is CH or N; A1 is R1, OR1. NHR1, N(R1)2, NHC(O)R1, NHC(O)NHR1, NHC(O)N(R1)2, NHC(O)OR1, C(O)NHR1, C(O)N(R1)2, C=NOR1, or C(NH2)NOC(O)R1;
