1159955-22-2Relevant academic research and scientific papers
Chiral phosphoric acid catalyzed enantioselective aza-Michael addition of aromatic amines to nitroolefins
Yang, Lei,Xia, Chungu,Huang, Hanmin
scheme or table, p. 1573 - 1576 (2012/07/03)
Chiral phosphoric acid was found to be an effective organocatalyst in the enantioselective aza-Michael addition of aromatic amines to nitroolefins giving the corresponding β-nitroamine products in good yields (65-95) with moderate to good enantiomeric excess (16-70). This study represents the first example of a chiral phosphoric acid catalyzed asymmetric aza-Michael addition reaction.
