1159992-75-2Relevant academic research and scientific papers
Inhibition of γ-secretase activity by helical β-peptide foldamers
Imamura, Yuki,Watanabe, Naoto,Umezawa, Naoki,Iwatsubo, Takeshi,Kato, Nobuki,et al.
supporting information; experimental part, p. 7353 - 7359 (2009/10/16)
Alzheimer's disease (AD) is a neurodegenerative disorder pathologically characterized by extensive extracellular deposition of amyloid-β (Aβ) peptides as senile plaques, and inhibition of "amyloidogenic" amyloid precursor protein (APP) processing by γ-sec
