1160038-58-3Relevant academic research and scientific papers
Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial β-carbonic anhydrases Rv1284 and Rv3273
Güzel, ?zlen,Maresca, Alfonso,Scozzafava, Andrea,Salman, Aydin,Balaban, Alexandru T.,Supuran, Claudiu T.
experimental part, p. 4063 - 4067 (2009/12/28)
A series of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides has been derivatized by reaction with 2,4,6-trimethylpyrylium perchlorate, leading to pyridinium derivatives. The new sulfonamides were evaluated as inhibitors of two β-carbonic anhydrases
Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII
Guezel, Oezlen,Maresca, Alfonso,Scozzafava, Andrea,Salman, Aydin,Balaban, Alexandru T.,Supuran, Claudiu T.
experimental part, p. 2931 - 2934 (2010/01/16)
A series of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides possessing various 2-, 3- or 4- substituted phenyl groups with methyl-, halogeno- and methoxy-functionalities, or a perfluorophenyl moiety, has been derivatized by reaction with 2,4,6-trime
