1160168-06-8Relevant academic research and scientific papers
A convenient synthesis of novel functionalized pyrimido[5′,4′: 4,5]thieno[3,2-c]pyridazines and related fused systems
Aly
experimental part, p. 3079 - 3096 (2009/10/15)
Possible approaches to the synthesis of functionalized, pyrimido[5′,4′:4,5]thieno [3,2-c]pyridazines 2-18, pyridazino[3′,4′:4,5]thieno[2,3-d]triazines 19, 20a,b and pyrido[3′,2′:4,5]thieno[3,2-c]pyridazines 22a,b are described. The sequence involves the heterocyclization of 6-amino-1,3-diphenyl-1,4- dihydrothieno[3,2-c]pyridazine-7-carboxamide (1) with appropriate reagents. The antimicrobial activity of some the newly synthesized compounds was examined. All tested compounds proved to be active as antibacterial and antifungal agents. Copyright Taylor & Francis Group, LLC.
