1160184-17-7Relevant academic research and scientific papers
PYRIDINE DERIVATIVES AS 5-HT6 RECEPTOR ANTAGONISTS
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, (2014/09/03)
Compounds of formula (I), wherein X, Y, Z, R1-R7, m and n are as defined herein, exhibit 5-HT6 antagonistic activity and are thus useful for the treatment of certain CNS disorders. Methods of use of said compounds are also provided.
New mixed Li/Mg and Li/Mg/Zn amides for the chemoselectlve metallation of arenes and heteroarenes
Rohbogner, Christoph J.,Wunderlich, Stefan H.,Clososki, Giuliano C.,Knochel, Paul
experimental part, p. 1781 - 1795 (2009/09/05)
New mixed Li/Mg and Li/Mg/Zn amides have been synthesized starting from readily prepared secondary amines. They allow a highly chemoselective directed magnesiation or zincation of various polyfunctional aromatics and heteroaromatics. The kinetic basicity, solubility and stability of these new bases have been compared with those of the corresponding 2,2,6,6- tetramethylpiperamide-derived bases. Wiley-VCH Verlag GmbH & Co. KGaA.
