1160246-84-3 Usage
Molecular structure
The compound has a spiro[3.5]nonane core structure with an oxa and an aza bridge, a carboxylic acid group, a 2-(iodoMethyl) group, and a 1,1-diMethylethyl ester group.
Chemical classification
It is an ester derivative of 1-Oxa-7-azaspiro[3.5]nonane-7-carboxylic acid.
Usage
It is primarily used in the pharmaceutical industry.
Therapeutic potential
The compound has potential therapeutic applications.
Chemical properties
The presence of the 2-(iodoMethyl) group and the 1,1-diMethylethyl ester group may impart specific chemical properties to the molecule.
Biological properties
The specific chemical structure of the compound may influence its pharmacokinetics and pharmacodynamics, affecting its biological activity.
Further research
More research and development is needed to fully understand the potential uses and implications of this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1160246-84-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,0,2,4 and 6 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1160246-84:
(9*1)+(8*1)+(7*6)+(6*0)+(5*2)+(4*4)+(3*6)+(2*8)+(1*4)=123
123 % 10 = 3
So 1160246-84-3 is a valid CAS Registry Number.
1160246-84-3Relevant articles and documents
Oxa-spirocycles: synthesis, properties and applications
Badlo, Valentyn R.,Bolbut, Andrii V.,Borysko, Petro,Diachuk, Taras,Dmytriv, Yurii V.,Fominova, Kateryna,Granat, Dmitry,Iminov, Rustam,Kovalchuk, Igor,Kuznetsova, Anastasiia S.,Kuznietsova, Halyna,Levterov, Vadym V.,Litskan, Eduard,Meliantsev, Vladyslav,Mykhailiuk, Pavel K.,Pavlova, Olexandra,Pishel, Iryna,Ripenko, Vasyl,Savchuk, Taras,Semeno, Volodymyr V.,Shvydenko, Kostiantyn,Svitlychnyi, Oleksiy,Tolmachev, Andrei A.,Vaskevych, Alla I.,Vaskevych, Ruslan I.,Vilchynskyi, Vladyslav,Vysochyn, Daniil
, p. 11294 - 11305 (2021/09/08)
A general approach to a new generation of spirocyclic molecules - oxa-spirocycles - was developed. The key synthetic step was iodocyclization. More than 150 oxa-spirocyclic compounds were prepared. Incorporation of an oxygen atom into the spirocyclic unit dramatically improved water solubility (by up to 40 times) and lowered lipophilicity. More potent oxa-spirocyclic analogues of antihypertensive drug terazosin were synthesized and studiedin vivo.
