1160355-48-5Relevant academic research and scientific papers
COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION
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Paragraph 0104, (2014/03/21)
This invention relates with anti-tumor activities of new compounds containing an adamantyl group or analogs thereof. The invention also relates with the medication applications of anti-tumor and other diseases by this kind of compounds with the combination of S, P, T structures containing adamantyl group and the formation of stereoisomer, tautomers, prodrug, pharmaceutically acceptable salts, complex salts or solvates to their anticancer application and anticancer agents, which have the following general formula:
Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines
Duque, Maria D.,Camps, Pelayo,Profire, Lenuta,Montaner, Silvia,Vazquez, Santiago,Sureda, Francesc X.,Mallol, Jordi,Lopez-Querol, Marta,Naesens, Lieve,Clercq, Erik De,Radhika Prathalingam,Kelly, John M.
experimental part, p. 3198 - 3206 (2009/09/27)
The synthesis of several (2-oxaadamant-1-yl)amines is reported. They were evaluated as NMDA receptor antagonists and several of them were more active than amantadine, but none was more potent than memantine. None of the tested compounds displayed antivira
