116041-19-1

Basic information

• Product Name: 3-Pyrrolidinecarboxamide, 5-oxo-1-(phenylmethyl)-
• Synonyms: 3-Pyrrolidinecarboxamide, 5-oxo-1-(phenylmethyl)-
• CAS NO: 116041-19-1
• Molecular Formula: C₁₂H₁₄N₂O₂
• Molecular Weight: 218.26
• Mol File: 116041-19-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyrrolidinecarboxamide, 5-oxo-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyrrolidinecarboxamide, 5-oxo-1-(phenylmethyl)-(116041-19-1)
• EPA Substance Registry System: 3-Pyrrolidinecarboxamide, 5-oxo-1-(phenylmethyl)-(116041-19-1)

Safety Data

• Hazardous Substances Data: 116041-19-1(Hazardous Substances Data)

Upstream product

• 51535-00-3 methyl 1-benzyl-5-oxo-3-pyrrolidinecarboxylate 

Downstream Products

• 368429-69-0 4-amino 1-benzylpyrrolidin-2-one 
• 93138-61-5 C-(1-benzyl-pyrrolidin-3-yl)-methylamine 
• 18471-40-4 1-Benzyl-3-aminopyrrolidine 

Relevant articles and documents

A convenient route to 1-benzyl 3-aminopyrrolidine and 3-aminopiperidine

1-Benzyl 3-aminopyrrolidine 1 and 1-benzyl 3-aminopiperidine 2 were prepared rapidly mainly in aqueous conditions in 55 and 75% yields, respectively, on a multi-gram scale starting from inexpensive and commercially available starting materials. The key step involved the Curtius rearrangement mediated by sodium nitrite and trifluoroacetic acid of the appropriate acylhydrazides. All the reactions (except LAH reductions) were performed in water.