1160463-75-1Relevant academic research and scientific papers
Regiospecific syntheses of 6a-(1 R-hydroxyoctyl)penicillanic acid and 6β(1 R-hydroxyoctyl)penicillanic acid as mechanistic probes of class D β-lactamases
Testero, Sebastian A.,O'Daniel, Peter I.,Shi, Qicun,Lee, Mijoon,Hesek, Dusan,Ishiwata, Akihiro,Noll, Bruce C.,Mobashery, Shahriar
supporting information; experimental part, p. 2515 - 2518 (2009/10/18)
The unique hydrophobic surface patches in class D β-Mactamases presented an opportunity for designing two compounds, 6α-(1R-hydroxyoctyl) penicillanic acid and 6β-(1R-hydroxyoctyl)penicillanic acid, as mechanistic probes of these enzymes. In a sequence of
