1160488-44-7

Basic information

• Product Name: O-(1,3-diphenylpropyl)hydroxylamine
• Synonyms: O-(1,3-diphenylpropyl)hydroxylamine
• CAS NO: 1160488-44-7
• Molecular Weight: 227.306
• Mol File: 1160488-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: O-(1,3-diphenylpropyl)hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: O-(1,3-diphenylpropyl)hydroxylamine(1160488-44-7)
• EPA Substance Registry System: O-(1,3-diphenylpropyl)hydroxylamine(1160488-44-7)

Safety Data

• Hazardous Substances Data: 1160488-44-7(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 100-58-3 phenylmagnesium bromide 
• 14097-24-6 1,3-diphenylpropan-1-ol 

Relevant articles and documents

Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase

Tryptophan (Trp) catabolizing enzymes play an important and complex role in the development of cancer. Significant evidence implicates them in a range of inflammatory and immunosuppressive activities. Whereas inhibitors of indoleamine 2,3-dioxygenase-1 (IDO1) have been reported and analyzed in the clinic, fewer inhibitors have been described for tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase-2 (IDO2) which also have been implicated more recently in cancer, inflammation and immune control. Consequently the development of dual or pan inhibitors of these Trp catabolizing enzymes may represent a therapeutically important area of research. This is the first report to describe the development of dual and pan inhibitors of IDO1, TDO and IDO2.