1160496-28-5

Basic information

• Product Name: C₂₃H₁₉Cl₂NOS
• CAS NO: 1160496-28-5
• Molecular Weight: 428.382
• Mol File: 1160496-28-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₁₉Cl₂NOS(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₁₉Cl₂NOS(1160496-28-5)
• EPA Substance Registry System: C₂₃H₁₉Cl₂NOS(1160496-28-5)

Safety Data

• Hazardous Substances Data: 1160496-28-5(Hazardous Substances Data)

Upstream product

• 34250-61-8 2-amino-5-ethoxybenzenethiol 
• 19672-60-7 3-(2-chlorophenyl)-1-(4-chlorophenyl)-2-propenone 

Relevant articles and documents

Syntheses of 1,5-benzothiazepines: Part XXXVI - Syntheses and antimicrobial evaluation of 2-(2-chlorophenyl)-4-(4-chlorophenyl/2-thienyl)-2,5-dihydro-8- substituted-1,5-benzothiazepines

Six 5-substituted-2-aminobenzenethiols have been reacted with 3-(2-chlorophenyl)-1-(4-chlorophenyl)-2-propenone and 3-(2-chlorophenyl)-1-(2- thienyl)-2-propenone in dry ethanol saturated with dry HCl gas, to obtain twelve new compounds, 8-substituted-2-(2-chlorophenyl)-4-(4-chlorophenyl/2-thienyl)-2, 5-dihydro-1,5-benzothiazepines in satisfactory yields. The structures of the final products have been assigned by elemental microanalyses data for elements, C, H, and N and by IR, 1H NMR, and mass spectroscopies. The synthesized compounds have been evaluated for their relative antimicrobial activity against the gram-positive bacteria, Staphylococcus aureus, gram-negative bacteria, Pseudomonas aeruginosa and the fungus, Candida albicans. The compounds have been found to show little antibacterial activity, but interestingly, showed significant antifungal activity. Copyright Taylor & Francis Group, LLC.